[citation needed] Locke and her husband, Rosario "Saro" Gullo, a Sicilian chef, lived and worked in Los Angeles, California.

[3] While in New York, Locke appeared in several off-Broadway productions,[dubious – discuss] and landed a role on the long-running soap opera As The World Turns.

Locke's television work includes shows such as Castle, Bones, The Mentalist, Windfall, CSI: NY, and Beverly Hills, 90210.

She has appeared in a number of movies made for television, including Black Widow, Final Approach and Born in the USA.

From Scratch was later adapted by producer Reese Witherspoon and writer Marguerite MacIntyre into a limited series starring Zoe Saldana for Hello Sunshine, 3 Arts, Cinestar and Netflix.