Temple Anshe Hesed is a Reform Jewish synagogue located at 5401 Old Zuck Road in Erie, Pennsylvania, in the United States.

In his history of the region, Samuel Bates reports that eight to ten members of this congregation began meeting in 1858.

[2] Built in 1882, the congregation's first synagogue was "a brick structure trimmed in stone and an ornament to the city".

Rabbi M. Wertzel, also known as M Wurzel, then served the congregation twice for a total of approximately fourteen years.

The most recent to serve have been Rabbis Randall M. Falk, Leonard Zion, Bernard Perlmuter, Lewis Littman, Bradley N. Bleefeld, Samuel Weinstein, Michael L. Feshbach, John L. Bush, and, from 2015 to 2018, Emily Ilana Losben-Ostrov.