State Route 70 (SR 70) is a state-maintained highway in East Tennessee, beginning at the border with North Carolina in the midst of the Cherokee National Forest and the Great Smoky Mountains and ending at the Virginia border in the extremely rural and mountainous terrain of Hancock County.

It goes west, crossing the Appalachian Trail a few hundred feet across the border before going through some mountains before lowering down into the farmland of Greene County and turning north, straightening and widening into a 2-lane rural highway with a speed limit of 55 (mph).

They then come to an intersection with SR 351 (which is also Tennessee State Route 107 Cutoff, an auxiliary Route of SR 107) before leaving South Greene at a crossing of the Nolichucky River, just a few yards away from the historic Nolichucky Dam and its reservoir, Davy Crockett Lake.

Shortly afterwards, they come to another intersection, where SR 70 separates and turns north, returning to a 2-lane highway and leaving Greeneville.

SR 70 then weaves through some more mountains before finally turning west to enter farmland again and widen and straighten into a 2-lane rural highway with a speed limit of 55 (mph).

They then enter Rogersville and pass through a business district and some neighborhoods before coming to an interchange with Main Street (Old US 11W), which connects the highway to downtown to the northeast as SR 66/SR 70 bypass it to the southwest.