As of the 2018 fall semester, Tennessee Tech enrolls more than 10,000 students,[4] and its campus has 87 buildings on 235 acres (95 ha) centered along Dixie Avenue in northern Cookeville.

TTU emphasizes a focus in STEM degrees but also provides infrastructure for traditional programs including liberal arts and nursing.

[26] Student Samuel Dowlen suffered severe injuries and temporary paralysis in August of 2009, during fraternity pranks in Phi Gamma Delta's inflatable pool.

[27] The Tennessee Tech athletic program is a member of the Ohio Valley Conference (OVC) and competes in the NCAA Division I Football Championship Subdivision.

In the academic year 2014/15, they produced a selection of at least five plays, among them Krapp's Last Tape, The Vagina Monologues, and A Midsummer Night's Dream.

[29] The playhouse attracted news coverage in the summer of 2022, when the local Upper Cumberland Pride, the Lambda Gay-Straight Alliance, and the Tech Players staged a drag performance in the on-campus theater.

[34] Henderson Hall is listed on the National Register of Historic Places, The building was designed by Benjamin F. Hunt, who worked for the noted regional architect R. H.