Tepelenë District (Albanian: Rrethi i Tepelenës) was one of the 36 districts of Albania, which were dissolved in July 2000 and replaced by 12 newly created counties.

[1] It was in the south of Albania, and its capital was the city of Tepelenë.

Its territory is now part of Gjirokastër County: the municipalities of Tepelenë and Memaliaj.

At the Vjosa (Greek:Aoos) Narrows ("Aoi Stena") in the district, a Macedonian army barred the way to Epirus and, in 198 BC, a decisive battle, the Battle of the Aous, took place between a Roman army commanded by Consul Titus Quinctius Flamininus and the Macedonians commanded by Philip V. After an attempt of a truce and an inconclusive battle, a shepherd led the Roman army to a point where the Macedonians could be attacked and the Romans won the battle.

This article about a specific location in Gjirokastër County, Albania, is a stub.