Termas de Río Hondo is a spa city in Santiago del Estero Province, Argentina.

It is located on the banks of the Dulce River, 65 km north of the provincial capital Santiago del Estero, near the artificial Río Hondo Lake.

The hot springs (Spanish: termas, Quechua: yacu rupaj) of the area have a temperature of over 30 °C (86 °F), and have made the town a popular spa resort for Argentines, who enjoy the waters recommended against high blood pressure and rheumatism.

Two public pools, La Olla and the Pileta Municipal, are near the town centre, along with many well-regarded hotels and restaurants.

This article about a place in Santiago del Estero Province, Argentina is a stub.