Suggs is a seven-time Pro Bowl selection, a two time All-Pro, and was named NFL Defensive Player of the Year in 2011.

While growing up in Saint Paul, he played youth football, as a center, with future major league MVP baseball player Joe Mauer as quarterback.

He later transferred to Hamilton High School where he set the Arizona Class 5A record for rushing yards in a game with 367 against Yuma Kofa as a junior in 1999.

[6] As a senior, Suggs was named a Parade high school All-American in 2000, Gatorade Arizona Player of the Year, the No.

[38] He initially filed a grievance because the team had designated him as a LB with the franchise tag rather than a DE, which resulted in a monetary difference of about $800,000.

On May 13, 2008, he reached an agreement with the team to split the difference in the franchise tag amounts of a LB and a DE and drop his grievance.

[39] In Week 7 of the 2008 NFL season, Suggs intercepted a pass from Chad Pennington of the Miami Dolphins and returned it 44 yards for a touchdown, the first pick six of his professional career.

[42] At season's end, he was named to his third Pro Bowl after producing 68 tackles (53 solo), two forced fumbles and eight sacks to go along with the two interceptions, a new career-high nine pass break-ups and two touchdowns.

[43][44] During the 2008–09 NFL playoffs, Suggs recorded sacks in all three of the Ravens' post-season games, including two in the AFC Championship against Ben Roethlisberger and the division-winning Pittsburgh Steelers.

[52] In the playoff win over the Kansas City Chiefs in the Wild Card Round, he made four tackles (all solo) and two sacks.

Against the Pittsburgh Steelers in the Divisional Round, he recorded six tackles (five solo), a career-high three sacks, and a forced fumble that was recovered and returned for a touchdown by fellow defensive end Cory Redding, but the Ravens would go on to lose 24–31 after squandering a 21–7 halftime lead.

[65][66] They had their season ended by the New England Patriots in the AFC Championship after a dropped touchdown by Lee Evans and a notorious missed field goal by Billy Cundiff.

[73] On October 20, 2012, Suggs was removed from the physically unable to perform (PUP) list, allowing him to play the next day against the Houston Texans.

[74] Suggs' return surprised many, as he finished the game with four tackles (three solo), one pass defended, and one sack, less than five and a half months after having Achilles tendon surgery.

[76] Suggs was key in the Ravens win over the Denver Broncos in the Divisional Round of the playoffs with two sacks on Broncos quarterback Peyton Manning, after which, the Ravens advanced to New England in a rematch of the previous year's AFC Championship Game where they defeated the New England Patriots by a score of 28–13.

[89] With the hit, Suggs became the 31st player in NFL history to register over 100 sacks,[90] and the first member of the Baltimore Ravens to achieve such a milestone.

[citation needed] In the Ravens' season finale, Suggs recorded a sack, a defended pass and a fumble recovery, all on Browns first-time-starting quarterback Connor Shaw.

The ball bounced off the hands of running back Ben Tate, the intended receiver on the play, and landed between a diving Suggs's legs.

The Ravens won this game 30–17 and moved onto the Divisional Round against the New England Patriots, where they lost to the eventual Super Bowl champions.

[97] In the regular season opener against the Denver Broncos on September 13, 2015, Suggs suffered an achilles injury and left the game.

[100] In the 2017 season opener against the Cincinnati Bengals, Suggs recorded two sacks and forced a fumble off of quarterback Andy Dalton in the third quarter of the 20–0 victory.

The fumble, which was recovered by teammate Michael Pierce, occurred in the Ravens' red zone and helped preserve the eventual shutout victory.

[101] In Week 2, against the Cleveland Browns, he forced a fumble off DeShone Kizer, which helped set up the Ravens' offense on an eventual touchdown scoring drive in the 24–10 victory.

[102] In Weeks 11 and 12, he had two sacks in each game, helping the Ravens win back-to-back times against the Green Bay Packers and Houston Texans.

Cardinals head coach Kliff Kingsbury said the team wanted to go with the younger players, and said the decision to release Suggs was a mutual agreement.

[119] Suggs was enticed to sign with the team after speaking with head coach Andy Reid, and was excited at the prospect of playing with reigning MVP Patrick Mahomes.

[125][126] Suggs wore a Star of David on his cleats during a game in October 2019 to commemorate the one-year anniversary of the deadly Tree of Life – Or L'Simcha Synagogue shooting in Pittsburgh.

[130] Apparently the parties had a disagreement during the tournament, and it was claimed that Suggs swung at the victim and broke his nose and cheekbone.

[137] On April 10, 2024, Suggs was arrested in Scottsdale, Arizona on charges of threatening and intimidating, as well as disorderly conduct with a weapon.