He has been involved a variety of eco-business pursuits in the Winnipeg area, including being president of Sustainable Development International, and serving as chairman of the Manitoba Clean Environment Commission.

He was president and CEO of the Gateway North Marketing Agency, which is responsible for ensuring the survival of the Port of Churchill and the Hudson Bay Rail Line.

He is also the founding president of the International Centre for Infectious Diseases, a not-for-profit organization created after the outbreak of SARS to support and enhance the mandate of the Public Health Agency of Canada.

From 1995 to 1997, he was president and CEO of Gateway North International, working to secure a future for the rail line that leads to the Port of Churchill.

Duguid had been part of the original task force that set out to make recommendations to improve Canada's response to infectious disease outbreaks in the wake of the SARS epidemic of 2003, especially in Toronto.

[7] Duguid was appointed the government lead for the efforts to clean-up Lake Winnipeg by Catherine McKenna, Minister of Environment and Climate Change, in November 2017.

[8] He would direct $25.7 million in federal spending which flow through the Lake Winnipeg Basin Program to address toxic algae blooms.