[4] After college, Kiser returned to his hometown Omaha and worked as an engineer for three years while acting in amateur productions; more than fifty plays.

His first two years in New York City included an array of small parts, ranging from theater to television to commercials.

[5][2] Becoming a life member of The Actors Studio,[6] Kiser was a regular on several soap operas, The Secret Storm and The Doctors.

It was during the 1970s and early 1980s that Kiser appeared in Three's Company, Hardcastle and McCormick, One Day at a Time, The Love Boat, Night Court, 227, Maude and The Golden Girls.

In the 1990s, he appeared on Walker, Texas Ranger, The Golden Girls, The Fresh Prince of Bel-Air, Lois & Clark: The New Adventures of Superman (as H. G. Wells) and Will & Grace.