Serpico was born in Fort Sill in Lawton, Oklahoma, the youngest of three children.

[1][better source needed] He became interested in acting after graduating from high school.

[5] Serpico married Kadia Saraf on June 8, 2022, in Beacon, New York.

[6] They met on set of Law & Order: Special Victims Unit.

He played Mickey Mantle in the ESPN miniseries The Bronx Is Burning.