Tezukayama University has two campuses—one in Gakuen-mae (学園前) in Nara city, and the other in eastern Ikoma (東生駒).

Tezukayama Gakuen was founded with an ideal of creating a new college town in Nara in celebration of Osaka's Tezukayama Gakuin 25th anniversary in 1941.

In 1964, Tezukayama University was established as a woman's college with the Faculty of Liberal Arts.

The Graduate School of Humanities at Tezukayama University is notable in the studies of Traditional Japanese Culture.

The junior college was affiliated with Tezukayama University from 1964 to 2005.