Sindikubwabo was born in Zivu, Shyanda village, in the town of Butare, formerly called Astrida in Rwanda-Urundi Territory, and currently the southern province of Rwanda.

Following the takeover by Juvénal Habyarimana, Sindikubwabo became a practising pediatrician in Kigali Central Hospital.

[citation needed] Taking advantage of his medical knowledge, he advised the military to cut a certain vein on the jugular to cause certain death.

[3] Following the invasion of the Rwandan Patriotic Front that took control of the country and ended the genocide, Sindikubwabo fled to Zaire (now the Democratic Republic of the Congo), where he lived in exile in Bukavu.

He died in exile in the Democratic Republic of the Congo in March 1998 and was never charged by the International Criminal Tribunal for Rwanda.