Thérèse Desqueyroux is a 1962 French drama film directed by Georges Franju, based on the 1927 novel of the same name by François Mauriac.

Thérèse Desqueyroux lives in a mansion in Argelouse in the Landes, a region in Southwestern France, unhappily married to Bernard, a dull and pompous landowner whose only interest is preserving his family name and property.

When Anne falls in love with Jean Azevedo, a young man from the neighbourhood, her parents ask Thérèse to intervene, as he is not acceptable as a future son-in-law because of his Jewish ancestry.

The concerned Bernard agrees to let her live freely in Paris with an allowance, on condition that she returns for family events as his spouse.

The film, which moved the novel's temporal setting from the 1920s to the 1960s but maintained the locale of Southwestern France,[2] was shot at Franstudio, Paris Studio Cinéma, and in the communes of Bazas, Villandraut, and Uzeste.