Thabiso Sesane (born 30 May 2000) is a South African soccer player who plays as a defender for South African Premier Division side Orlando Pirates.
From Snake Park in Soweto, he began his career at Orlando Pirates and played with their reserve team Pele Pele in the PSL Reserve League.
In the 2021-22 season he played in the Motsepe Foundation Championship for Jomo Cosmos.
After returning to Orlando Pirates he helped the club win the 2023–24 Nedbank Cup and the 2024 MTN 8.
[6] He was called-up to the South Africa national football team for their 2025 AFCON qualification matches against Congo on 11 and 14 October 2024.