It is called the Battle of I-10 because the two universities are located along Interstate 10 connecting Las Cruces and El Paso.

Following World War II, the series resumed on an annual basis from 1946 until 2001, when UTEP's administration made the controversial decision to cancel their scheduled trip to Las Cruces in favor of scheduling an additional home contest against a Division I-AA opponent.

The schools agreed to meet again in 2002 (a 49–14 New Mexico State win, their biggest blowout of the Miners since 1922), but did not play again until 2004 in El Paso when the Miners exacted revenge for their blowout loss two years prior with a 45–0 pasting of the Aggies, the most lopsided result in the series in 55 years.

On November 5, 2021, New Mexico State announced it would be joining UTEP in Conference USA in all sports including football starting in 2023.

The programs both experienced their greatest national prominence in the late 1960s and early 1970s, when both schools were led by young up-and-coming coaches who would eventually win more than 700 games (Lou Henson at New Mexico State, Don Haskins at UTEP) and appeared in the NCAA tournament's Final Four within four years of each other.

Both programs returned to national prominence in the early 1990s with the Aggies and Miners both advancing to the NCAA Tournament's "Sweet Sixteen" in 1992.

The Aggies defeated the Miners 89–73 in the first meeting of the 2011–12 season series on November 19, 2011, at the Pan American Center in Las Cruces.