115 entrants participated in Super Smash Bros. Melee singles and the event was won by Oscar "Lovage" Nilsson.

Prior to the tournament, top Swedish player Leffen was denied entry into the United States at customs because of lack of a proper work visa due to his affiliation with an American company, Team SoloMid.

Ultimate was featured for the first time, and was won by Sota "Zackray" Okada over Samuel "Dabuz" Buzby.

[20] There were also smaller Super Smash Bros. Brawl and Wii U side events, respectively won by Hunter "Player-1" Rogers over Will "Lain" Vetter and Brenden "ShyDude" King over "AFMbot".

The tournament was again cancelled after they received a cease and desist letter from Super Smash Bros. publisher Nintendo.

[21][22] The Big House returned to an offline format for its tenth iteration, held on October 7–9, 2022. at the Huntington Place in Detroit as part of the Nintendo-sponsored Panda Cup.

Melee was won by Masaya "aMSa" Chikamoto over Joseph "Mango" Marquez, marking the first time "aMSa" and a Yoshi player won a major tournament in the game's competitive lifespan; Cody "iBDW" Schwab, Zain Naghmi and Miles "Soonsay" Foster qualified for the Melee bracket of the Panda Cup Finale.

[23][24][25][26] As with the previous tournament, there were smaller Brawl and Wii U side events, respectively won by Christina "Chia" Korsak over "Merrick" and "Mr. Spikes" over "Arico".