The film was directed by King Vidor and produced by Victor Saville for Metro-Goldwyn-Mayer British at Denham Studios.

After his laboratory and notes are destroyed by the miners, he moves to London, treating working-class patients in impoverished conditions.

Dr. Philip Denny, Manson's best friend and still working for improved working-class health, dies at the hands of an incompetent, social-climbing surgeon.

In the original text, the character of Christine Manson is killed off in a road accident at the point when she and her husband have begun to address problems in their relationship.

[2] The film was nominated for Oscars in four categories: Best Picture, Best Actor (Robert Donat), Directing, and Adapted Screenplay.