The novel deals with Bunny Munro, a middle-aged lothario, whose constant womanising and alcohol abuse comes to a head after his wife's suicide.

[1] The novel was also released as an audiobook, using a 3D audio effect, produced and sound-directed by British artists Iain Forsyth and Jane Pollard, with a soundtrack by Nick Cave and Warren Ellis, and in a number of e-book formats, including an iPhone application that synchronised the audiobook with the text and included exclusive videos of Cave reading.

A series of live events took place in late 2009 to promote the book under the title of "A Night with Nick Cave", combining music, readings and a Q&A session with the audience.

In November 2023, a six-part television series adaptation of the novel was announced by Sky Studios with Matt Smith playing Bunny.

Moreover, The Death of Bunny Munro has received strong reviews from the British media: Graeme Thomson (writing in The Observer, 6 September 2009) awarded the novel 4 stars out of 5.