"The Disintegration Machine" is a science fiction short story by British writer Arthur Conan Doyle.

Professor Challenger, a big burly man, is arguing with people who are persistently calling him on the telephone when his young friend Malone, a reporter for The Daily Gazette, enters and requests Challenger accompany him to inspect the discovery of Theodore Nemor, who claims to have invented a machine capable of disintegrating objects.

In a fury, Challenger assaults Nemor, throws him to the floor and threatens his life should he not restore the professor to his previous state.

Nemor boasts that in the hands of the Russians, who were the highest bidder for the rights to the invention, London and its millions of inhabitants could be destroyed.

Challenger claims that a small amount of electricity is leaking from the chair on which he sat when he was disintegrated.