[2] The song has since become associated with professional wrestler Roderick Strong, who has used End of Heartache as his theme song on numerous occasions, most recently in All Elite Wrestling, Along With Model Sai Bennett, Who Used The End of Heartache In Ring Of Honor.

The video edit of the song features mostly clean singing from vocalist Howard Jones with a few background screams, much like the video for "My Curse".

The first video shows the band performing the song inter-cut with footage from Resident Evil: Apocalypse along with close-up shots of the band playing.

[5] The song was included on Revolver's list of "16 Great Non-Hair-Metal Power Ballads".

[6] The song was nominated for Best Metal Performance at the 47th Annual Grammy Awards, but lost to Whiplash by Motörhead.