The Fifth Plague of Egypt is an 1800 oil painting by Romantic English artist Joseph Mallord William Turner currently in the permanent collection at the Indianapolis Museum of Art.

To the right, Moses stands with his arms outstretched, cursing the Egyptians with a plague of hail and fire, far away from the engulfed city.

In the background, tumultuous clouds swirl above the Egyptian city, which is denoted by the gleaming, white pyramid in the centre of the canvas.

Turner submitted this large-scale painting to the annual Royal Academy exhibition in London in 1800.

The twenty-four-year-old Turner was eager to impress the London art critics, with the largest canvas submitted by a young artist.