[2] The Fluffer features cameos from a number of figures in the adult entertainment industry, including Ron Jeremy, director Chi Chi LaRue,[3] Karen Dior, Zach Richards, Derek Cameron, Chad Donovan, Thomas Lloyd, Jim Steel, Chris Green and Cole Tucker.

On his first shoot, Sean ends up as a "fluffer" for Johnny, performing (offscreen) oral sex on him to help him maintain an erection and reach orgasm for the "money shot".

He learns that Johnny's real name is Mikey, he is "gay-for-pay" and doesn't perform oral sex on other men or even kiss.

Meanwhile, Johnny's girlfriend Julie, who works as a stripper under her stagename Babylon but who has tried to move into mainstream acting, learns she is pregnant.

An expensive video camera goes missing at the studio, and company manager Chad Cox is found dead in his apartment.

Sean shares in oblique terms memories of being sexually abused as a child by an adult male neighbor.

Sean initially tries to hitchhike back to the United States, but ends up accepting an offer to go farther south to San Ignacio, an idyllic location he had previously suggested he and Johnny visit.

Mikey survives in Mexico by committing armed robberies, his new gritty reality counterpointed as Sean reads a fan letter written to Johnny, who remains a figure of fantasy.