Contributors included Stookie Allen and Boody Rogers, as well as Charles Curtis, Ed Hermes, Howard Williamson, F. N. Litten, Kenneth Whipple, Charles Driscoll, Joe Archibald, Sidney Garber, Earle Danesford, Hafon, J. Molina, Bencho, Gil King, and Buford Tone.

[10] A rival to Eastern Color's successful comic-book series Famous Funnies,[9] it similarly reprinted newspaper comic strips, mostly NEA-syndicate comics such as Alley Oop, by V. T. Hamlin, and Captain Easy, by Roy Crane, as well as others including Mutt and Jeff, by Bud Fisher, Tailspin Tommy, by Hal Forrest,[9] Flapper Fanny Says by Gladys Parker, and Annibelle by Dorothy Urfer.

[12] The Funnies began running original material with Mayer's feature Scribbly, about a boy cartoonist, laid out to look like a Sunday newspaper comic strip.

Art Nugent's single-page puzzle and game feature, called either Home Magic or Everybody's Playmate, ran in issues #1–27.

Following Gaines and Mayer leaving to produce work for All-American Publications, most reprints other than Alley Oop were abandoned in favor of original content, including "Mr. District Attorney", based on the radio series, and "John Carter of Mars", adapted from the Edgar Rice Burroughs series of novels, and after a few issues illustrated by his son, John Coleman Burroughs.