It's Garry Shandling's Show is an American television sitcom that originally aired on Showtime from September 10, 1986, to May 25, 1990.

The series, created by Garry Shandling and Alan Zweibel, is notable for breaking the fourth wall.

In the series, Garry Shandling plays a stand-up comedian who is aware that he is a television character.

The series stars Garry Shandling as himself: A neurotic, sardonic stand-up comedian who just happens to be aware he is a television sitcom character.

Garry spends just as much time interacting with the studio audience as he does the regular cast members, performing monologues and show-closing summations of the episode's events (much like George Burns on The George Burns and Gracie Allen Show).

On America's presidential election night in 1988, Showtime presented a live episode wherein Shandling brought in Soul Train host Don Cornelius to incorrectly announce that Michael Dukakis had soundly defeated George H. W. Bush.

Considered a critical and niche success,[3] It's Garry Shandling's Show ran 72 episodes and was on the air for four seasons (1986–1990).

While fighting ovarian cancer, Gilda Radner guest-starred as herself in the series in 1988 in what would be her final television appearance.