It was serialized on Square Enix's Gangan Online manga website from May 2018 to October 2022.

Written and illustrated by Tsumuji Yoshimura, The Gender of Mona Lisa was serialized on Square Enix's Gangan Online manga website from May 14, 2018 to October 3, 2022.

[2][3] The series' chapters were compiled into ten tankōbon volumes from September 21, 2018 to December 12, 2022.

[6][7] During their Anime Expo 2023 panel, Square Enix Manga & Books announced that they would begin publishing the series under the title Just Like Mona Lisa in July 2024.

[8] The series was nominated for the sixth Next Manga Awards in the web category and was ranked 20th out of 50 nominees.