[1] Affiliated with Washington University School of Medicine and the Alvin J. Siteman Cancer Center, the McDonnell Genome Institute is creating, testing and implementing new approaches to the study of genomics with the goal of understanding human health and disease, as well as evolution and the biology of other organisms.

The McDonnell Genome Institute makes all sequence data available to the research community, pending appropriate quality analysis.

The department established Opportunities in Genomics Research whose purpose is to increase the number of underrepresented minorities who obtain Ph.D.s in the field of genomics/genetics.

The McDonnell Genome Institute is located on the Washington University School of Medicine campus in St. Louis, Missouri, at 4444 Forest Park Avenue.

[7] The data center also houses a legacy 1,200-square-foot (110 m2) server room equipped with raised floors, redundant power and cooling.