The Girl from Chicago is a lost[1] 1927 American synchronized sound criminal romantic drama film directed by Ray Enright and starring Myrna Loy and Conrad Nagel.

While the film has no audible dialog, it was released with a synchronized musical score with sound effects using the Vitaphone sound-on-disc process.

The film was produced and distributed by the Warner Bros. and is based upon a short story by Arthur Somers Roche that appeared in the June 1923 Redbook.

In order to get her brother exonerated, Mary travels to New York and pretends to be a Chicago gun moll.

He attempts to help Mary prove her brother's innocence, and the two of them are caught in a fierce gun battle between the crooks and the cops.