The Great Sioux Uprising is a 1953 American Technicolor western film directed by Lloyd Bacon and starring Jeff Chandler, Faith Domergue and Lyle Bettger.

During the Civil War, in Wyoming, horse dealers Joan Britton (Faith Domergue) and Stephen Cook (Lyle Bettger) are competing to supply the Union Army with horses.

[2] Alexis Smith and Stephen McNally were meant to co star with Chandler.

[4] McNally's wife then fell ill and he asked to withdraw from the film; he was replaced by Lyle Bettger.

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