The Heart, She Holler is an American horror comedy television series created by Vernon Chatman and John Lee from PFFR for Cartoon Network's nighttime programming block Adult Swim.

[1] The series premiered on November 6, 2011 and ended on December 11, 2014, with a total of 28 episodes over the course of 3 seasons.

The series, described as "Southern Gothic drama"[2] and "an inside-out blend of soap opera and politically incorrect surrealist comedy",[3] is about the long-hidden and isolated son of the Heartshe dynasty (Patton Oswalt) returning to run the town and being locked in conflict with sisters Hurshe (Kristen Schaal and Amy Sedaris) and Hambrosia (Heather Lawless).