For the editing process, directors do not receive final cut, and Duplass screens the episodes to a group of 20 people who work at their company for feedback.

The site's critical consensus reads, "Room 104 uses its anthology structure to its advantage, telling a series of short, eclectic stories that hit their marks more often than they miss.

He wrote, "the variety of storytelling on display builds such tingly anticipation, each new episode is worth it even when the narrative disappoints" and that it is "such remarkable, refreshing television that even when it's bad, it's good".

A 42-year-old guest, whose wife wants to split up with him, seeks advice from the ghost of his college best friend who accidentally drowned in his early twenties.

In 1969, the sole (apparent) survivor of a plane crash finds herself in the room, covered in mud, cuts and bruises.

A young woman finds herself unable to escape a series of increasingly disturbing nightmares, some involving her mother.

Decades in the past, a brother and sister have a tense meeting regarding the development of the hotel that will contain Room 104, complicated by the arrival of a demonic transient.

A man with a mysterious skin condition records a series of increasingly revelatory video messages for his doctor.

Following an apocalyptic event, a traumatized teenage girl and a psychically gifted scavenger find common ground in their struggle for the future.

A documentary about real-life father and son artists who, invited to use the Room 104 set as a canvas, discuss the personal struggles in their past and the nuances of their craft.

A dying man with unique abilities attempts to settle his affairs with his daughter, who was reluctant to learn his powers, and his son, who misused them.

Left alone, a teenage girl makes prank calls to entertain herself, but one takes a very dark turn spurred on by her alternate personality.

Two actors who co-created a 1970s horror television series reunite and discuss their falling out, but when old tensions resurface, the show proves to be much more than mere fiction.

Fifty years after a woman sells her soul to the devil to live a rebellious rock-and-roll lifestyle, she strikes a mutually beneficial deal with his disgruntled assistant.

When exposure to a mysterious plant specimen transforms Room 104 into a lush jungle ecosystem, a scientist tries desperately to preserve the phenomena within.