The programme was on air from February 2001 to March 2011 and was broadcast each weekday morning between 10:00am and 12:45pm, and later 13:00-16:00 each weekend afternoon.

And Bank Holidays And Good Fridays At 10.00–13.00 The show began at 10:00am and lasted for two and three quarter hours every day.

In addition the show had a number of features as well as guests and live music performances from well-known artists.

This included elements of the evening show, such as tour dates and occasional live 'sessions' at Maida Vale Studios while working within the restrictions of Radio 1's daytime schedule.

In July 2008 The Jo Whiley Show was fined £75,000 for misleading listeners, along with other BBC programmes totaling £400,000 [1] The incident involved a member of BBC staff posing as a member of the public taking part in a competition.