It was released on 24 July 2009 as the third and final single from Miller-Heidke's second studio album, Curiouser (2008).

The song, initially not intended for release as a single, was used in promo advertisements for Australian soap opera Neighbours, and in result it began selling digitally by peaking at number 2 on iTunes.

In 2009, "The Last Day on Earth" was nominated for Single of the Year at the 2009 ARIA Awards.

[2] The song was also used on the show Piers Morgan's Life Stories on 31 October 2009, in a segment where Dannii Minogue as a guest discussing sister Kylie's cancer.

The music video was filmed by Mark Alston in a house on the Northern Beaches of Sydney and released on 3 August 2009 through the official Miller-Heidke page on Facebook.