As of April 2024, the St Stephen's Green museum was "temporarily closed", with its operators reputedly planning to "reopen shortly" at an alternative venue on Dublin's Pembroke Street.

The Little Museum, the "brainchild" of director Trevor White and curator Simon O'Connor, was formed in April 2011 and officially opened its doors to the public in October of the same year.

As of 19 March 2014, the Little Museum and the National Library of Ireland were the joint owners of a collection that includes private letters and previously unseen sketches, paintings, and poems.

[6] Exhibitions in the museum include displays covering the 1916 Rising, U.S. President John F. Kennedy's visit to Dublin, and many other events in Irish political and social history.

Over 1,000 such local "ambassadors" were sought to advise visitors on "underestimated" attractions in Dublin, and included historians, teachers, writers and other ordinary city residents.