The Mad Doctor of Market Street is a 1942 American horror film produced by Universal Pictures starring Lionel Atwill.

[3] The film was a low-budget project that utilized the studio's contract players and gave rising director Joseph H. Lewis an opportunity to demonstrate his versatility with little production money.

[10] From contemporary reviews, Lee Mortimer of The New York Daily News declared the film to be "on a par with all the other mad doctor mellers which have been shown on the Rialto screen.

"[6] William Boehnel of The New York World-Telegram called the film "a really bad piece of workmanship" and that it had a "story so bogus, so labored, so dreary, the dialogue is so unfunny and the acting so embarrassing that the whole thing is in a class by itself.

"[6] From retrospective reviews, the authors of Universal Horrors declared the film to be "a foolish but occasionally entertaining little time-killer if viewed with low expectations.

"[1] Hal Erickson of AllMovie found that "the fact that it was the only Universal horror film directed by cult favorite Joseph H. Lewis, it's a shame that Mad Doctor of Market Street isn't better than it is."

[13] Writing for Famous Monsters of Filmland in 1962, Joe Dante, Jr. included Mad Doctor of Market Street on his list of the worst horror films of all time.