It also serves as a continuation of the 1994–1997 PBS Kids series The Magic School Bus, with Lily Tomlin reprising her role as Ms. Frizzle.

She then hires her younger sister, Miss Fiona Frizzle, to teach the class, and passes the keys of the Magic School Bus over to her.

The kids journey on exciting new field-trips, discovering new locations, creatures, time periods and more to learn about the wonders of science, educating viewers along the way, on the eponymous Magic School Bus.

[19][20] The episode endings feature question and answer sessions with Professor Frizzle, echoing the segments about viewers calling the producer which accompanied the original series on commercial-free channels.

Common Sense Media deemed the show a worthy successor to its 1990s sister series, praising its gender and ethnic diversity and its commitment to teaching children about STEM subjects.

[33] Christianity Today argues that the show managed to keep the "genius of the franchise", which is that the children are almost more intrigued by the complexity and order of the natural world rather than the magic of the titular school bus.

[34] Daily Dot praised the series' premiere for addressing the change to the show's structure, putting viewers at ease through the transition, adding that the science was made "approachable".

[36] Another AV Club article wrote that the series is "lively, fast-paced, and exceedingly tolerable for adults", and full of enough science to allow them to park their kids in front of it guilt-free.