The Mouse and the Motorcycle is a children's novel written by Beverly Cleary, illustrated by Louis Darling and published in 1965.

Ralph longs for a life of danger and speed, wishing to get away from his relatives, who worry about the mice colony being discovered.

While Keith and his family explore California, Ralph recklessly rides the motorcycle through the depths of the hotel.

One night he is spotted by Keith's mother, who initially thinks she is imagining things, but later is sure that she saw a mouse riding a motorcycle.

Churchill Films produced an adaptation of The Mouse and the Motorcycle directed by Ron Underwood in 1986, featuring Mimi Kennedy and Ray Walston, which aired as an episode of ABC Weekend Special.