The sequel to The Nut Job (2014) and based on the characters created by Peter Lepeniotis, it stars the voices of Will Arnett, Maya Rudolph, Jackie Chan, Katherine Heigl, Bobby Moynihan, Bobby Cannavale, Isabela Moner, Jeff Dunham, and Gabriel Iglesias.

Since Norvirus Raccoon's defeat, Surly Squirrel is now loved by Liberty Park's urban wildlife community, who oversees an all-you-can-eat buffet at Maury's Nut Shop (now renamed Nibbler's Nut Shop), but this worries Andie as she has a more hard-working outlook on life than Surly.

Andie suggests returning to their roots by foraging for food in Liberty Park as Surly and Buddy fail to find other food-packed places.

Andie attempts to convince the animals to work hard for food, which Surly believes can result in disappointment.

Surly becomes caught in one of Gunther's traps and the animals are pursued by Muldoon's dog Frankie who later falls in love with Precious.

While searching for Muldoon's car, Surly and Buddy run afoul of a colony of territorial white mice led by Mr. Feng.

Andie, Jimmy, Johnny, and Jamie find what seems to be a suitable park, but it turns out to be a golf course that almost gets them killed.

Muldoon tries to escape the chaos using a hot air balloon, but Surly and Buddy commandeer a roller coaster to catch up to him.

Additional voices by Emma Dale, Jamie Denis, Jonathan Dixon, Lukas Engel, Dave Fennoy, Jess Harnell, Dwayne Hill, Julie Lemieux, Josh Robert Thompson, and Kari Wahlgren.

[8] Will Arnett, Gabriel Iglesias, Jeff Dunham, Katherine Heigl and Maya Rudolph reprised their roles.

[23] The marketing campaign of The Nut Job 2: Nutty by Nature included promotions, such as Carl's Jr, Blue Diamond Almonds, Menchies, National Wildlife Federation, Humane Society of the United States, iFetch, Kika, Homes.com, Frontier Airlines, PB Crave, National Recreation and Park Association, and Pug Nation of Los Angeles, while the TV campaign includes the major networks, and cable outlets such as Cartoon Network, Disney XD, Nickelodeon, USA, TBS, Univision and Telemundo.

[7] In the United States and Canada, The Nut Job 2: Nutty by Nature was released alongside Annabelle: Creation and The Glass Castle, and was initially projected to gross $12–14 million from 4,003 theaters in its opening weekend.

[26] The Nut Job 2: Nutty by Nature completed its theatrical run in the United States and Canada on September 28, 2017.

The site's critical consensus reads, "The Nut Job 2: Nutty by Nature may be a slight improvement over its predecessor, but its frantic animated antics still offer minimal entertainment to all but the least discriminating viewers.

[24] Owen Gleiberman of Variety wrote: "As an animated entertainment, The Nut Job 2 lacks several key factors: memorable characters, a fun story, jokes that will appeal to adults as well as little kids.