Sajak's announcer and sidekick on the show was Dan Miller, his friend and former colleague from their time working together in the mid-1970s at WSM-TV (now WSMV-TV) in Nashville, Tennessee.

The in-studio band was led by jazz musician Tom Scott, who subsequently served the same role on the short-lived Chevy Chase Show.

The house band members were: Tom Scott (saxes), Jerry Peters (piano), Barnaby Finch (keyboards), Art Rodriguez (drums), Tim Landers (bass), Eric Gale, Carlos Rios, or Pat Kelley (guitar), and Dave Koz (saxes, flute, and the EWI—electronic wind instrument).

Its format emulated Carson's model, featuring a monologue, comedy bits, interviews with celebrities, and performances by musicians and comedians.

The woman denounced Limbaugh's anti-abortion statements earlier in the show, stating "women's lives are more important than any potato" and "You don't know what it's about.

After a commercial break, Limbaugh attempted to address the topic of affirmative action, but was heckled again by several male audience members wearing ACT UP T-shirts, calling him a "murderer" before he could make a point.

Limbaugh sat silently with the camera focused on him for nearly a minute while audience members continued shouting phrases such as "You want people to die!"

He stated that the audience was not "evicted from the studio" or "forcibly restrained from doing anything they did" and gave CBS credit for handling the situation in the manner it did.

More than a decade later, Sajak (serving as guest host of Larry King Live) interviewed Limbaugh and facetiously said the show "was going so well that they actually auditioned replacements for me on the air.