Jack Benny, Mel Blanc, Andy Devine, Martin and Lewis, Don Wilson, and Ed Kemmer & Lyn Osborn (Commander Corry & Cadet Happy, of Space Patrol).

In The Big Broadcast 1920–1950 Frank Buxton and Bill Owen wrote: "Even though many people thought that The Fitch Bandwagon was lucky to be sandwiched in between Jack Benny at 7pm and Edgar Bergen at 8pm on NBC, the [show] pioneered Sunday evening entertainment programming, because prior to its appearance most broadcasters felt that Sunday programming should be of a more religious or serious nature.

Playing themselves as radio and music star parents of two precocious young daughters (played by actresses Jeanine Roose and Ann Whitfield, instead of the Harrises' own young daughters), Harris refined his character from the booze-and-broads, hipster jive talker he had been on the Benny show into a vain buffoon but loyal husband who usually needed rescuing by Faye, his occasionally tart but always loving wife.

The show's writers, Ray Singer and Dick Chevillat, also used Faye's experience making the ill-fated film Fallen Angel as a source of meta-gags, writing her as a rich, in-demand starlet.

In what is seen by historians as an ironic jab at her former studio, announcer Bill Forman closed each program with "Alice Faye appears through the courtesy of 20th Century Fox."

In truth, Faye's contract had been torn up when she walked out rather than abide Darryl Zanuck cutting her scenes in favor of Linda Darnell.

The first 14 episodes of season eight (1953–1954), were written by a team of writers, singly and in pairs/trios: Ed James, Ray Brenner, Lou Dermon, Jack Douglas, Marvin Fisher, Frank Gold, Al Schwartz, and Phil Shuken.

Legendary character actor Gale Gordon appeared frequently as Mr. Scott, the slightly pompous and withering fictitious representative of actual sponsor Rexall.

One running gag involved Scott's affected disdain for Harris, seeing his continued employment as an unfortunate necessity in order to keep Alice Faye on the show.

Another involved Harris's continuous mis-identification of the Rexall brand (naming the company's trademark colors as pink and purple, rather than their familiar blue and orange, for example)—when he remembered them at all.

Few episodes went without two music interludes, usually an upbeat or novelty number by Harris in his friendly baritone and a ballad or soft swinger by Faye in her affectionate contralto.

The theme song was the 1926 jazz standard Sunday (music by Chester Conn; lyrics by Jule Styne, Bennie Krueger, and Ned Miller).

Though their on-air personae were that of a bumbling husband and exasperated wife, Harris and Faye's genuine love for each other was evident both on and off the air.

NBC offered the couple (as well as Fred Allen) a lucrative new deal to stay, though occasionally Harris would allude to Benny's network switch on the Harris-Faye show.

At the height of their radio show's popularity, the couple made a memorable appearance on the CBS mystery hit, Suspense, on the May 10, 1951 episode called "Death on My Hands".

[citation needed] Jeanine Roose, who portrayed Alice Jr. on the program, said about Lewis: "He and Phil would play off each other all the time; they had such good rapport and a genuine liking for each other.

[13] Child impersonator Walter Tetley played obnoxious delivery boy Julius, who had sarcastic one-liners and malicious troublemaking for Harris and Remley, and a crush on Faye whom he often called his soulmate.