[6] The film stars Russell Crowe as Amorth, with Daniel Zovatto, Alex Essoe, and Franco Nero in supporting roles.

Amorth replies that evil does exist and that he did not perform an actual exorcism but rather, some psychological theater to help the mentally ill man.

He learns that a founder of the Spanish Inquisition, an exorcist, was possessed, and left to die in a cage buried underground.

Amorth also finds the Church covered this up and eventually discovers the name of Henry's demon, Asmodeus, which will assist the exorcism.

The triumphant duo visit Rome and find Sullivan has taken leave in Guam, being replaced by Lumumba.

In October 2020, Screen Gems acquired the rights to the story of Father Gabriele Amorth with Ángel Gómez hired to direct.

[12] Chester Hastings and R. Dean McCreary were attached to write the script, while Michael Patrick Kaczmarek, Jeff Katz, and Edward "Eddie" Siebert were set to produce the film.

[13] In June 2022, Julius Avery boarded the film as director along with producer Doug Belgrad of 2.0 Entertainment.

[14] Subsequent script revisions were provided by Michael Petroni, Evan Spiliotopoulos, and Chuck MacLean.

[11] Principal photography took place from August to October 2022 in Dublin and Limerick, Ireland and Rome, Italy.

[4][5] In the United States and Canada, The Pope's Exorcist was released alongside Renfield, Mafia Mamma, Sweetwater, and Suzume, and was projected to gross between $4–10 million from 3,178 theaters in its opening weekend.

The Pope's Exorcist is standard-issue holy horror in most respects, but its star's sanctified performance will be the answer to some viewers' prayers.

Yet a body representing the real-life practitioners depicted in new Russell Crowe horror The Pope's Exorcist have condemned the film as 'unreliable … splatter cinema'.

In a statement issued last month, the International Association of Exorcists (IAE) called the title of the film 'pretentious' and claimed that its Da Vinci Code-esque conspiratorial plot poses 'unacceptable doubt' to the public as to who 'the real enemy is, the devil or ecclesiastical power'.

Chris Vognar of Rolling Stone positively reviewed his performance, writing that "Crowe brings an imposing physicality and winking charm to go with Amorth's gravity.