[6][7] It features a large number of special guests and is the only Fishbone album released on Disney's Hollywood Records.

Whereas the band's previous album, the angry Chim Chim's Badass Revenge, contained some of the band's heaviest moments, Psychotic Friends Nuttwerx is full of sunny reggae, ska and pop hooks that make it the most accessible Fishbone album to date.

of Bad Brains, Gwen Stefani, George Clinton, Rose Stone, Rick James, Flea, John Frusciante and Chad Smith of Red Hot Chili Peppers, Durga McBroom, best known for her work with Pink Floyd, and many others.

LA Weekly called the album "a funk-o-ramic magnum opus.

"[8] The Chicago Reader wrote that the "jittery, giggly, and thoroughly funky comeback attempt ranges from painstaking old-fashioned hand-constructed R & B to slinky reggae to a loving but violent mangling of Sly & the Family Stone's 'Everybody Is a Star.