[4] The game itself centers around three main (playable) characters: Brandeis, an enhanced human and "freelance hacker"; Donovan, an implantless human and owner of The Red Strings Club; and Akara-184, an android formerly owned by Supercontinent to administer implant surgery to customers and who possesses advanced empathy capabilities.

[5] Donovan, Brandeis, and Akara-184 are working together to stop Supercontinent from releasing a system known as Social Psyche Welfare, which alters the minds of all implanted humans in order to eliminate emotions such as anger and depression; Donovan's interactions with Akara-184 and employees of Supercontinent encourages the player to consider the role of and extent to which technology should alter one's humanity.

While playing as Akara-184 within a Supercontinent Ltd. facility, the player crafts different sets of implants made of biomass via pottery wheel that are to be inserted in clients, based on what will best help their careers or desires.

Danielle Riendeau of Vice considered it offensive to use a deadname as a clue and criticized making someone's gender identity a plot twist.

[13] Paula Ruiz, a developer of The Red Strings Club who is transgender, said it is important to denounce deadnaming but that "it's also a part of trans people's realities" and the game's usage was not frivolous.