The series focuses on the lives and duties of staff members at fictional Chastain Park Memorial Hospital in Atlanta, Georgia, with generally a critical eye into real life bureaucratic practices of the healthcare industry.

Created by Amy Holden Jones, Hayley Schore, and Roshan Sethi, the series was purchased by Fox from Showtime in 2017.

[8] In August 2016, it was announced that Showtime was developing a new original series, known as The City, pitched by executive producer Antoine Fuqua.

"[21] It was also announced that Amy Holden Jones would produce the series and co-write the pilot episode along with Hayley Schore and Roshan Sethi.

[3] Phillip Noyce, an executive producer for the series, directed the first two episodes of the season after signing a multi-year deal with 20th Century Fox Television.

[28] On March 13, 2019, however, series co-creator Amy Holden Jones stated on her Twitter and Instagram accounts that there were 23 episodes in season 2.

[36] Matt Czuchry, Emily VanCamp, Shaunette Renée Wilson and Melina Kanakaredes were later announced to be starring in the series as well.

[37][38][39][40] Moran Atias was also cast for the role of Renta Thorpe, CEO at Chastain Park, which was originally portrayed by Valerie Cruz in the pilot.

[9] The following day, it was announced that Moran Atias, Merrin Dungey and Melina Kanakaredes would not be returning,[10] and that Jane Leeves would also be joining the cast as a regular for the second season on a one-year contract.

[57] Exterior and some interior shots of the High Museum of Art in midtown-Atlanta were used as the backdrop for the fictional Chastain Park Memorial Hospital.

The site’s consensus reads: “With sporadic amusement and a handful of decent performances, The Resident drifts between medical melodrama and hospital horror with often unintentionally funny results.”.

[105] USA Today rated the series 1.5 out of 4 stars stating "It's a shame, because it's a waste of the talents of Czuchry and VanCamp (Revenge), two usually appealing TV veterans" and "The Resident can't save itself".

[106] Meanwhile, TVLine rated the series a B+ and said: "The Resident takes a hard look at the thorny ethical issues surrounding today's health-care providers.