The film has a main title montage consisting of comic book covers set to Creedence Clearwater Revival's "Born on the Bayou", and features Dick Durock and Louis Jourdan reprising their roles as Swamp Thing and Anton Arcane respectively, along with Sarah Douglas and Heather Locklear.

In an attempt to stave off the effects of aging, Dr. Arcane, assisted by Dr. Lana Zurrell, combines genes from various swamp animals and human beings, creating an army of monsters known as Un-Men.

Dr. Arcane captures Abby to use in his genetic experiments, but she is rescued by Swamp Thing, formerly scientist Alec Holland who was transformed into a bog creature after a confrontation with the evil doctor and his henchmen a few years earlier.

[4] In 2008, Dick Durock told Bullz-Eye.com that the suit made filming difficult: "I hated the thought of having to go through the whole thing of wearing 50, 60, 70 pounds of weight in the summertime in Savannah, Georgia, but the money was there, and it's a job".

[5] According to BPA, Locklear had a hard time working with the guy who played Swamp Thing in his human form: "The model was full of himself and really rubbed Heather the wrong way.

[9] Vincent Canby of The New York Times gave a negative review, proclaiming the film "is intended for people who missed the 1982 Swamp Thing and don't want the bother of renting the videocassette".

[10] A writer for Time Out gave a somewhat neutral review, stating that "Wynorski is well-versed in double-bluffing his audience, denying them the chance of balking at dreadful special effects by implying that the ineptitude is deliberate.

He opts for cheap nostalgic laughs and camp '50s sci-fi scenery; depending on whether you find this funny, you'll either smile knowingly or gasp in disbelief".

[12] Cinapse also gave the positive review as "The Return Of Swamp Thing is a humorous and oddly sweet action adventure that wants nothing more than to entertain you with its quirkiness from start to finish".