The series begins as Mary Lennox (played by Sarah Hollis Andrews) is abandoned by her parents and native attendants at her home in India due to a devastating outbreak of cholera.

One night, upon hearing distant crying, Mary leaves her room to investigate and discovers her cousin, Colin.

After a tragic fall caused her grave injuries, an early labour, and the birth of a sickly Colin, Lilias died.

In Lord Craven's grief, he closed the garden away and hid the key, avoiding his son and sad memories of his wife's death.

Colin's father Archibald, on receiving a letter from Mrs. Sowerby to return home, and experiencing a dream in which Lilias tells him to go to the garden, rushes back to the manor and finds Mary, Dickon, and his son Colin in the beautiful and blooming garden -- healthy, strong, and restored to health.