Guest stars announced for the season include former series writer Conan O'Brien, John Cena, Danny DeVito, Tom Hanks, and Andy Serkis.
In the finale, Bart's 11th birthday approaches and he realizes that Springfield is changing around him: Principal Skinner leaves for Sacramento with Groundskeeper Willie, Mr. Burns passes away and his fortune is given to the power plant employees, Comic Book Guy and his wife Kumiko's baby is born, with John Cena assisting with the delivery, Moe's Tavern closes, Nelson's father and the real Seymour Skinner return, Krusty the Clown ends his show, and Chief Wiggum joins the Chicago Police Department, as well as various marriages and deaths.
But when they discover he was scammed and are thrown out only 20 minutes later, the family squat in a room designated for the luggage of a rich newly-wed named Tasha, whose new husband is Sideshow Bob.
Lisa decides that this culture is her future instead of Springfield and is swept away into a surreal journey through Capital City’s art and drama scene only to soon discover things aren't as they seem.
While Grampa tries to avoid his past, a curious Lisa pushes him to reopen the cold case that caused in the disappearance of his partner Billy and involved both Agnes Skinner and Mr. Burns.
A series of scary stories are prefaced by "Cottage of Terror", a Mexican-themed opening animated by Jorge R. Gutierrez: Guest stars: Juan Carlos Enriquez, Jorge R. Gutierrez and Tim Yoon sing "Jarabe Tapatío" and Rob LaZebnik as Spit-Takers Anonymous Guy An assortment of stories involving the female residents of Springfield like Luann Van Houten, Malibu Stacy, Mrs. Muntz, Marge, Patty and Selma, Bernice Hibbert, Mama Risotto, Lunchlady Dora, Lisa, Agnes Skinner, Helen Lovejoy, and Rayshelle Peyton.
In an ode to the works of Ray Bradbury, the Simpson family attend a carnival where Lisa meets an individual known as The Illustrated Man who uses his tattoos to weave various stories for her.
Guest star: Andy Serkis as Siegfried Blaze and The Illustrated Man The Simpsons mention at a Congressional hearing about the time when they were trapped on a flight with the most unruly passengers in America, some of which they know.
While Marge and the kids worry, Homer, Barney, Moe, Carl, Ned Flanders and Pin Pal newcomer Fausto try to survive the harsh natural elements of a frozen mountainside as they attempt the arduous journey back home.
[18] Selman said that the producers have agreed to most of Disney's asks for collaboration such as the real-time Simpsons animated version of the December 9, 2024 presentation of Monday Night Football.