The season will feature an ensemble cast of Leslie Bibb, Carrie Coon, Walton Goggins, Sarah Catherine Hook, Jason Isaacs, Lalisa Manobal, Michelle Monaghan, Sam Nivola, Lek Patravadi, Parker Posey, Natasha Rothwell, Patrick Schwarzenegger, Tayme Thapthimthong and Aimee Lou Wood.

[8] The third season's production was disrupted by the 2023 Writers Guild of America strike, resulting in the release being pushed to 2025.

[9][10] Upon the third-season renewal announcement, producers confirmed that there will be a new cast of characters in another White Lotus resort.

[12] In January 2024, it was announced that Leslie Bibb, Jason Isaacs, Michelle Monaghan, Parker Posey, Dom Hetrakul, Tayme Thapthimthong,[13] Carrie Coon,[14] Miloš Biković, Christian Friedel, Morgana O'Reilly, Lek Patravadi, Shalini Peiris,[15] Walton Goggins, Sarah Catherine Hook, Sam Nivola, Patrick Schwarzenegger, Aimee Lou Wood,[16] Francesca Corney, Nicholas Duvernay, and Arnas Fedaravičius joined the cast for the season.

[24] Principal photography began in February 2024, with locations including Bangkok, Phuket, and Ko Samui,[25][26][27][28] and wrapped in August 2024.