"Theme from S-Express" is an acid house song by British electronic dance music group S'Express, from their debut studio album, Original Soundtrack (1989), written and produced by Mark Moore and Pascal Gabriel.

For the North American release, some spoken word samples had to be removed due to licensing issues, and were recreated by unnamed voice artists.

"[5] Nancy Culp from Record Mirror named "Theme from S-Express" Single of the Week, adding, "Coming on all Seventies and Cerrone (who could forget 'Supernature'?)

"[6] The magazine's James Hamilton wrote in his dance column, "London DJ Mark Moore leads the Seventies flares fashion with a Rose Royce/BT Express-type buzzing bass synth and hissing hi-hat drive 117-0bpm semi-instrumental, full of samples, quotes and sound effects in current Eighties style, a likely hit.

[8] In 2020, The Guardian ranked the song number 51 in their list of "The 100 greatest UK No 1s",[9] writing, "To watch Top of the Pops as 1987 gives way to 1988 is to watch the freaks taking over the asylum: after MARRS and Bomb the Bass's earlier acid house hits, S-Express's sample-heavy track affirmed the sound's chart coronation, making the Stock Aitken Waterman stable look even more square, and stuck one in the eye of London's throttlingly cool club scene with its euphoric, queer collage.