Theophylact Bache (January 17, 1735 – October 30, 1807) was an American merchant and fifth president of the New York Chamber of Commerce.

His younger brother, Richard Bache, was the second Postmaster General of the United States and the son-in-law of Benjamin Franklin.

[1] He landed in New York 17 September 1751, took charge of the business of Paul Richard a successful merchant and former mayor, whose wife was a Bache relative.

He supported the first Continental Congress; but when the American Revolutionary War actually began he remained so far neutral as to incur the suspicions of the committee of safety.

He remained in New York during the British occupation of the city, and befriended American officers held there as prisoners of war.