Theridomorpha is an extinct clade of Palaeogene rodents that were endemic to western Europe and lived from the early Eocene to the late Oligocene.

It is proposed to belong to the suborder Ischyromyiformes, of which the Gliridae is the sole surviving family, and contains the families Euromyidae, Masillamyidae, Theridomyidae, and Pseudosciuridae.

[1] Theridomorphs had wide variations in both their tooth crown heights and their surface patterns, namely bunodont, lophodont, or selenodont dentitions.

Whereas Eocene species had brachyodont, or low-crowned, to slightly hypsodont (higher-crowned) dentitions, Oligocene species tended to have more semi-hypsodont dentitions.

Theridomorphs ranged in size from small field mice at 50 g (1.8 oz) to muskrats at 1 kg (2.2 lb).